In an example, a fluid collection device includes a fluid impermeable barrier that at least partially defines a chamber. The fluid impermeable barrier also defines an opening extending therethrough. The opening is configured to be positioned adjacent to a female urethra. The fluid collection device also includes a conduit at least partially disposed in the chamber. The conduit defines at least one aperture that provides fluid communication between an interior of the conduit and the chamber. The conduit also includes an outlet that provides fluid communication between the interior of the conduit and a vacuum source or a fluid storage container. The size and shape of the fluid collection device helps minimize the area of a user's skin both that contacts the device and to which a vacuum pressure is applied.