THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; INC.;AMGEN, INC.;AMGEN;THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
ALEX M DEPAOLI,ELIF ARIOGLU ORAL,SIMEON I TAYLOR,A. GARG
申请号:
PT10165256
公开号:
PT2219031E
申请日:
2002.10.22
申请国别(地区):
PT
年份:
2013
代理人:
摘要:
Leptin, leptin analogs, and leptin derivatives are used to treat patients with lipodystrophy. Leptin is effective against lipodystrophy conditions for both genetic and acquired forms of the disease. A therapeutically effective amount of leptin can be administered in a variety of ways, including in a vector comprising nucleic acid sequences encoding leptin. Methods of the present invention contemplate administration of leptin, leptin analogs, and leptin derivatives to patients having approximately 4ng/ml or less before treatment.