INC.;THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH OFFICE OF TECHNOLOGY;AMGEN, INC.;THE BOARD OF REGENT;AMGEN
发明人:
DEPAOLI ALEX M,ORAL ELIF ARIOGLU,TAYLOR SIMEON I,GARG A.,Depaoli Alex M,Oral Elif Arioglu,Taylor Simeon I,Garg A.
申请号：
SI200231031
公开号：
SI2219031T1
申请日:
2002.10.22
申请国别(地区):
SI
年份:
2013
代理人:
摘要：
Leptin, leptin analogs, and leptin derivatives are used to treat patients with lipodystrophy. Leptin is effective against lipodystrophy conditions for both genetic and acquired forms of the disease. A therapeutically effective amount of leptin can be administered in a variety of ways, including in a vector comprising nucleic acid sequences encoding leptin. Methods of the present invention contemplate administration of leptin, leptin analogs, and leptin derivatives to patients having approximately 4ng/ml or less before treatment.
