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Use of leptin to treat metabolic abnormalities associated with lipoatrophy
专利权人:
Abhimanyu Garg;Elif Arioglu Oral;Simeon I. Taylor;Alexander M. DePaoli
发明人:
Alexander M. DePaoli,Elif Arioglu Oral,Simeon I. Taylor,Abhimanyu Garg
申请号:
US13103294
公开号:
US08318666B2
申请日:
2011.05.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Leptin, leptin analogs, and leptin derivatives are used to treat patients with lipoatrophy. Leptin is effective against conditions of lipoatrophy for both genetic and acquired forms of the disease. A therapeutically effective amount of leptin can be administered in a variety of ways, including subcutaneously and using gene therapy methods. Methods of the present invention contemplate administration of leptin, leptin analogs, and leptin derivatives to patients having a leptin level of approximately 4 ng/ml or less before treatment.
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