CHO, Yong Hee,JANG, Won Young,UM, Jin Hee,CHOE, Dong Woon,KIM, Hyun Soo,KIM, Jung Hoon
申请号：
EP15838561
公开号：
EP3188720A4
申请日:
2015.08.31
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present disclosure relates to compositions for preparing an oral dispersible film comprising tadalafil or its pharmaceutically acceptable salt thereof, surfactant, plasticizer and sweetening agent an oral dispersible film and methods of preparing thereof. The oral dispersible film of the present disclosure can improve dissolution rate of the tadalafil without complicated processes and has superior stability compared to previous Cialis because generation of related compounds are inhibited regardless of existence of a packaging. Additionally, superior film properties comprising prevention of film breakage, securement of flexibility and prevention of oil leakage from film formulation can be maintained when comprising specific content of a polyethylene glycol 400 as the plasticizers.
