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Method for treating cerebral amyloid angiopathy using pharmacological chaperones to increase the activity of gangliosidases
专利权人:
Amicus Therapeutics; Inc.
发明人:
Brandon Alan Wustman,Kenneth Valenzano,Robert Boyd
申请号:
US14704445
公开号:
US09931353B2
申请日:
2015.05.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a method for treating an individual having Cerebral Amyloid Angiopathy by using pharmacological chaperones to increase the activity of gangliosidase and/or sialidase enzymes involved in ganglioside catabolism.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关专利
monoclonal antibody, light chain and heavy chain variable regions, isolated cdr, polynucleotide, therapeutic composition, methods for treating disease and disorder, for producing an antibody, for treating or alleviating the effects of disease and disorder, for reducing plaque burden in an individual's brain, to reduce the amount of plaque in an individual's brain, to decrease the total amount of soluble spruce in an individual's brain, to retain or increase an individual's cognitive memory capacity, to diagnose from or to diagnose a predisposition to an amyloid-associated disease or condition
SPECIFIC IN RELATION b-AMYLOID 1-42 MONOKLONALNI ANTIBODIES WHICH ARE THERAPEUTIC CHARACTERISTICS
アミロイドタンパク質を検出するためのシステムおよび方法
chimeric antibody or fragment thereof, or humanized antibody or fragment thereof, nucleic acid molecule, expression vector, cell, composition, methods of preventing, treating or alleviating the effects of one or more diseases, of diagnosing a disease or condition associated with amyloid in an individual, determining the extent of amyloidogenic plaque burden in an individual's tissue and / or body fluids, disaggregating preformed beta-amyloid fibers and preventing abet-induced neuron degradation, test, chain variable region, and cell lineage
MR IMAGE PROCESSING METHOD FOR DETECTING AMYLOID PLAQUES