chimeric antibody or fragment thereof, or humanized antibody or fragment thereof, nucleic acid molecule, expression vector, cell, composition, methods of preventing, treating or alleviating the effects of one or more diseases, of diagnosing a disease or condition associated with amyloid in an individual, determining the extent of amyloidogenic plaque burden in an individual's tissue and / or body fluids, disaggregating preformed beta-amyloid fibers and preventing abet-induced neuron degradation, test, chain variable region, and cell lineage
Andrea Pfeifer,Andreas Muhs,Maria Pihlgren,Ryan Watts
申请号:
BRPI0812478
公开号:
BRPI0812478A2
申请日:
2008.06.12
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The present application is related to chimeric and humanized antibody and to methods and compositions for the therapeutic and diagnostic use in the treatment of amyloidosis, a group of disorders and abnormalities associated with amyloid protein such as Alzheimer's disease.