EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION;이화여자대학교 산학협력단
发明人:
LEE, Kong Joo,이공주,LEE, Hee-Yoon,이희윤,LEE, Je Jin,이제진,KIM, Hwang Suk,김황석,SEO, Ji-wan,서지완,LEE, Hongsoo,이홍수,SHIN, Ji Soo,신지수,KIM, Bo-kyung,김보경
申请号:
KRKR2019/006519
公开号:
WO2019/231262A1
申请日:
2019.05.30
申请国别(地区):
KR
年份:
2019
代理人:
摘要:
The present invention provides a novel biphenyl derivative compound or a pharmaceutically acceptable salt thereof. A biphenyl derivative compound or a pharmaceutically acceptable salt thereof, according to the present invention, is a substance for enhancing Nm23-H1/NDPK activity and can inhibit metastasis and growth of cancer, thereby exhibiting excellent effects not only in prevention, improvement, and treatment of cancer, but also in inhibition of metastasis of cancer.La présente invention concerne un nouveau composé dérivé de biphényle ou un sel pharmaceutiquement acceptable de celui-ci. Un composé dérivé de biphényle ou un sel pharmaceutiquement acceptable de celui-ci, selon la présente invention, est une substance permettant d'améliorer l'activité de Nm23-H1/NDPK et pouvant inhiber la métastase et la croissance du cancer, ce qui présente d'excellents effets non seulement dans la prévention, le soulagement et le traitement du cancer, mais également dans l'inhibition de la métastase du cancer.본 발명은, 신규 바이페닐 유도체 화합물, 또는 이의 약학적으로 허용가능한 염을 제공한다. 본 발명에 따른 바이페닐 유도체 화합물, 또는 이의 약학적으로 허용가능한 염은 Nm23-H1/NDPK 활성 증진 물질로 암의 전이 및 성장을 억제할 수 있어 암의 예방, 개선 및 치료뿐만 아니라 암전이 억제에 우수한 효과를 나타낸다.