KIM, TAE KYUNG,金泰卿,WOO, JUNG WON,禹晶媛,LEE, JOAN YOON JI,李伦知,李倫知,AHN, YOUNG JOO,安永珠,CHA, JI-EUN,车志恩,車志恩,RHIM, HYOUYOUNG,林孝英,JANG, WOO ICK,张宇翼,張宇翼
申请号:
TW106129474
公开号:
TW201806614A
申请日:
2017.08.30
申请国别(地区):
TW
年份:
2018
代理人:
摘要:
The present disclosure relates to a method for administering a human growth hormone fusion protein (GX-H9) for treating growth hormone deficiency. Specifically, the present disclosure relates to a pharmaceutical composition for treating growth hormone deficiency, which comprises an hGH fusion protein (GX-H9) and a pharmaceutically acceptable carrier, wherein the fusion protein (GX-H9) is administered once a week at a dose of 0.4 to 1.6 mg per body weight kg of a pediatric patient, or administered once every two weeks at a dose of 0.8 to 3.2 mg per body weight kg of a pediatric patient. In addition, the present disclosure relates to a method for treating growth hormone deficiency, which comprising a step of administering an hGH fusion protein (GX-H9) to a patient with growth hormone deficiency once a week at a dose of 0.4 to 1.6 mg per body weight kg of the patient, or once every two weeks at a dose of 0.8 to 3.2 mg per body weight kg of the patient.本發明關於一種治療生長激素缺乏症的人類生長激素(hGH)融合蛋白(GX-H9)的方法。更具體地,本發明關於一種用於治療生長激素缺乏症的藥物組合物,包含 hGH融合蛋白與藥學上可接受的載體,其中融合蛋白按兒童患者每公斤體重0.4毫克至1.6毫克的劑量每週施用一次,或按兒童患者每公斤體重0.8毫克至3.2毫克的劑量每兩週施用一次。此外,本發明關於一種治療生長激素缺乏症的方法,包括向患有生長激素缺乏症的一患者施予一hGH融合蛋白,按每公斤體重0.4毫克至1.6毫克的劑量每週施用一次,或按每公斤體重0.8毫克至3.2毫克的劑量每兩週施用一次。