Organ and tissue preservation solutions having improved stability are disclosed. The solutions are comprised of two separate solutions. The first solution, Solution A, is comprised of a balanced salt solution that is stable in solution at a pH of 7.0 or above. A second solution, Solution B, is comprised of an aqueous solution containing L-glutathione and/or cysteinylglycine, a sugar such as D-glucose, L-Arginine, a reducing agent such as ascorbic acid and water at a pH of below 7.0, preferably from about 3.0 to 5.0. The two Solutions are then mixed together at the point of use and the pH adjusted to about 7.3 resulting in the organ and tissue preservation solution having improved stability. Preferably, solution A has a pH of about 7.6 and solution B has a pH of about 5.0. The present invention is also comprised of kits 20 that contain the two Solutions in two separate containers 22, 24. In an alternate embodiment, the sugar can be in Solution A.本發明揭示一種具有經改良之安定性之器官及組織保存溶液。該等溶液係由兩種不同之溶液組成。第一溶液(溶液A)係由可在pH為7.0或7.0以上之溶液中安定之平衡鹽溶液組成。第二溶液(溶液B)係由含有L-穀胱甘肽及/或半胱胺醯甘胺酸、糖(例如D-葡萄糖)、L-精胺酸、還原劑(例如抗壞血酸)及水之pH在7.0以下，較佳約3.0至5.0的水溶液組成。然後在使用時將該等兩種溶液混合在一起並將pH調整至約7.3，從而形成該具有經改良之安定性之器官及組織保存溶液。較佳地，溶液A具有約7.6之pH及溶液B具有約5.0之pH。本發明亦包括該等兩種溶液包含在兩個獨立容器(22,24)內的套組20。在一替代實施例中，該糖可存在於溶液A中。
