MORRISSON, CARL,PABLA, SARABJOT,CONROY, JEFFREY,NESLINE, MARY,GARDNER, MARK,HE, JI,GLENN, SEAN
申请号：
CA3039402
公开号：
CA3039402A1
申请日:
2017.10.06
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
A method for generating an immune score, the method comprising the steps of: (i) determining a qualitative and/or quantitative assessment of tumor infiltrating lymphocytes in a sample； (ii) determining a qualitative and/or quantitative assessment of T-cell receptor signaling in the sample； (iii) determining a qualitative and/or quantitative assessment of mutation burden in the sample； (iv) generating, using a predictive algorithm, an immune score based on the determined qualitative and/or quantitative assessment of tumor infiltrating lymphocytes, the determined qualitative and/or quantitative assessment of T-cell receptor signaling, and the determined qualitative and/or quantitative assessment of mutation burden.
