NATIONAL RESEARCH COUNCIL OF CANADA;OTTAWA HEALTH RESEARCH INSTITUTE
发明人:
GRIFFITH, MAY,CARLSSON, DAVID J.,LI, FENGFU
申请号:
CA2495132
公开号:
CA2495132C
申请日:
2003.08.11
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
A bio-synthetic matrix comprising a hydrogel which is formed by cross-linkinga synthetic polymer and a bio-polymer is provided. The matrix is robust,biocompatible and non-cytotoxic and is capable of supporting cell in-growth invivo. The matrix can be tailored to further comprise one or more bioactiveagents. The matrix may also comprise cells encapsulated and dispersed therein,which are capable of proliferating upon deposition of the matrix in vivo.Methods of preparing the bio-synthetic matrix and the use of the matrix invivo for tissue engineering or drug delivery applications are also provided.