WRAIR; a U.S. Army Research institution under the United States Government; as represented by the Secretary of the Army
发明人:
Alving, Carl R.
申请号：
AU2012209014
公开号：
AU2012209014A1
申请日:
2012.07.31
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2012209014A120120823.pdf#####C:\NRPortbJ\DCC\SZPW489512_ .DOC-31/07!2012 ABSTRACT Antibodies and method of making antibodies, either monoclonal or polyclonal wherein said antibodies have dual or multi-specific binding capacity to more than one type of antigenic epitope. The antibodies have simultaneous or independent recognition subsites to each of the epitopes. Antigenic epitopes include lipids, peptides, proteins, amino acid sequences, sugars and carbohydrates. Monoclonal antibodies and a method of making monoclonal antibodies of the invention include monoclonal antibodies that are broadly neutralizing to HIV-I or other envelop viruses wherein the monoclonal antibody has subsites that simultaneously recognize protein and lipid epitopes from the virus.1/10 4 0* 56 jF. 6 1
