Mahmood MOSHIRI,Kiarash MOSHIRI,Arsha MOSHIRI,Mohammad Hadi SEKHAVATI,Hassan MONHEMI
申请号：
US16643509
公开号：
US20200190480A1
申请日:
2018.08.28
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are polypeptide epitopes of aspartyl-(asparaginyl)-3-hydroxylase (“AABH”) as well as polyepitopes thereof. Also provided are antibodies that specifically bind these polypeptide epitopes and poly epitopes, as well as binding the aspartyl-(asparaginyl)-3-hydroxylase protein itself. The disclosure further provides methods of assaying for AABH polypeptide epitopes, cells expressing these polypeptide epitopes and the AABH protein. Also provided are methods of diagnosing cancer by the detection of AABH peptides and methods of treating cancer by targeting cells that express AABH.
