WRAIR; a U.S Army Research institution under the United States Government; as represented by the Secretary of the Army
发明人:
Alving, Carl R.
申请号：
AU2011244970
公开号：
AU2011244970B2
申请日:
2011.11.04
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2011244970B220120503.pdf#####C \NRPortb\DCCSZP\397059S_1.DOC-3/1112011 ABSTRACT Antibodies and method of making antibodies, either monoclonal or polyclonal wherein said antibodies have dual or multi-specific binding capacity to more than one type of 5 antigenic epitope. The antibodies have simultaneous or independent recognition subsites to each of the epitopes. Antigenic epitopes include lipids, peptides, proteins, amino acid sequences, sugars and carbohydrates. Monoclonal antibodies and a method of making monoclonal antibodies of the invention include monoclonal antibodies that are broadly neutralizing to HIV-I or other envelop viruses wherein the monoclonal antibody has 10 subsites that simultaneously recognize protein and lipid epitopes from the virus.1/10 5 Fi6 .1
