Referring to a pyrazole derivative Compound of formula (IB), where Cy is aryl cycloalkyl C3 C6 C8, C10, cicloalquenilo C3 - C8 N1 is an integer from 0 to 4 A1A is Halogen, Oh, carboxy, among others 2a is C1 - C3 alkyl C8 C8 alkyl, cycloalkyl - C1 - C6, among others CYA is (a), (b), among others m2 And M4 are 1, 2 or 3 m3 is 1, 2 or 3 N3 is 1 or 2 M5 is 0, 1 or 2 R3A is Oh, alkyl C1 - C6Among others, r3b is Oh, c1-c6 alkyl, among others n is 0, 1, 2, 3 or 4. Preferred compounds are: acid (3R, 4R) - 4 - methyl - 5 - oxopirrolidin carboxylic acid - 3 - [5 - (1 - phenyl - 3 - trifluorometoxifenil) - 1H pyrazole amide il] - 3 - [1 - (4-fluorophenyl) - 5 - (3 - (trifluoromethoxy) phenyl) - 1H pyrazole - 3 - il] amide acid (3R, 4R) - 4 - methyl - 5 - oxopirrolidin - 3 - carboxylic acid, among others.These compounds have Inhibitory activity of SGLT1 (Sodium - Glucose cotransporter 1)REFERIDA A UN COMPUESTO DERIVADO DE PIRAZOL DE FORMULA (Ib), DONDE Cy ES ARILO C6-C10, CICLOALQUILO C3-C8, CICLOALQUENILO C3-C8 n1 ES UN ENTERO DE 0 A 4 R1a ES HALOGENO, OH, CARBOXI, ENTRE OTROS R2a ES ALQUILO C1-C8, CICLOALQUILO C3-C8-ALQUILO C1-C6, ENTRE OTROS Cya ES (a), (b), ENTRE OTROS m2 Y m4 SON 1, 2 O 3 m3 ES 1, 2 O 3 n3 ES 1 O 2 m5 ES 0, 1 O 2 R3a ES OH, ALQUILO C1-C6, ENTRE OTROS R3b ES OH, ALQUILO C1-C6, ENTRE OTROS n2 ES 0, 1, 2, 3 O 4. SON COMPUESTOS PREFERIDOS: ACIDO (3R,4R)-4-METIL-5-OXOPIRROLIDIN-3-CARBOXILICO[1-FENIL-5-(3-TRIFLUOROMETOXIFENIL)-1H-PIRAZOL-3-IL]AMIDA, [1-(4-FLUOROFENIL)-5-(3-(TRIFLUOROMETOXI)FENILO)-1H-PIRAZOL-3-IL]AMIDA DEL ACIDO (3R,4R)-4-METIL-5-OXOPIRROLIDIN-3-CARBOXILICO, ENTRE OTROS. DICHOS COMPUESTOS TIENEN ACTIVIDAD INHIBIDORA DE SGLT1 (COTRANSPORTADOR DE SODIO-GLUCOSA 1)
