Methods of culturing sebocyte cells, isolated populations of sebocytes, and methods of using the cultured sebocyte cells for screening compounds that inhibit or activate lipogenesis are provided.Linvention concerne des procédés de culture de sébocytes, des populations isolées de sébocytes, et des procédés dutilisation des sébocytes cultivés pour le criblage de composés qui inhibent ou activent la lipogenèse.