Composés hétérocycliques condensés comme inhibiteurs de la 11-bêta-hydroxystéroïde déshydrogénase de type I

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专利权人:

Bristol-Myers Squibb Company

发明人:

申请号：

EP12163063.6

公开号：

EP2474549A1

申请日:

2008.04.16

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure:        W-L-Z     (I)or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W, L are defined herein andZ is selected from the following bicyclic heteroaryl groups:

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