Jun Li,James J. Li,Stephen P. OConnor,Haixia Wang,Lawrence J. Kennedy,Jeffrey A. Robl,Lawrence G. Hamann
申请号：
US12595524
公开号：
US08546394B2
申请日:
2008.04.16
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Novel compounds are provided which are 1 1-beta-hydroxysteroid dehydrogenase type I inhibitors. 1 1-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 1 1-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: W-L-Z or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W, L are defined herein and Z is selected from the following bicyclic heteroaryl groups: (a), (b), (c), (d).
