JUN LI,JEFFREY A. ROBL,JAMES J. LI.,LAWRENCE J. KENNEDY,HAIXIA WANG,JIE JACK LI,XINHUA QIAN,RAJENDRA P. DESHPANDE,LAXMA R. KOLLA,REGINALD O. CANN,CHENKOU WEI,MICHAEL GALELLA
申请号:
BRPI0817656
公开号:
BRPI0817656A2
申请日:
2008.09.19
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds of formula I: or stereoisomers or pharmaceutically acceptable salts thereof, wherein G, Q, X, Y, R3, R3a, and R3b are defined herein.