Jeffrey A. Robl;Jun Li;Michael Galella;Lawrence J. Kennedy;Haixia Wang;Jie Jack Li;James J. Li;Chenkou Wei
发明人:
Jun Li,Jeffrey A. Robl,James J. Li,Lawrence J. Kennedy,Haixia Wang,Jie Jack Li,Chenkou Wei,Michael Galella
申请号:
US13197273
公开号:
US08541444B2
申请日:
2011.08.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds of formula I:or stereoisomers or pharmaceutically acceptable salts thereof, wherein G, Q, X, Y, R3, R3a, and R3b are defined herein.