Zheming Ruan;Jeffrey A. Robl;Jun Li;Haixia Wang;Christopher B. Cooper;James J. Li;Lawrence G. Hamann
发明人:
James J. Li,Lawrence G. Hamann,Haixia Wang,Zheming Ruan,Christopher B. Cooper,Jun Li,Jeffrey A. Robl
申请号：
US12424674
公开号：
US08148396B2
申请日:
2009.04.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure:or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof wherein W, L, R3, R3a, R3b and R4 are defined herein.
