To provide a compound that inhibits TRPV4 activity and is useful for prevention or improvement of overactive bladder and irritable bowel syndrome or the like.SOLUTION: A TRPV4 activity inhibitor has a rosmarinic acid derivative selected from the formulae (Ia)-(Id) or a salt thereof as an active ingredient.SELECTED DRAWING: None【課題】TRPV4の活性を抑制し、過活動膀胱や過敏性腸症候群等の予防又は改善に有用な化合物の提供。【解決手段】下式(Ia)~(Id)から選ばれるロズマリン酸誘導体又はその塩を有効成分とするTRPV4活性抑制剤。【選択図】なし