PROBLEM TO BE SOLVED: To provide an inhibitor of activation of TRPV4 effective for preventing or improving bladder disorder such as overactive bladder.SOLUTION: An inhibitor of activation of TRPV4 includes flavonoids selected from isorhamnetin, catechin, hesperetin, quercetin, luteolin, fisetin, chrysin, genistein, and glycosides of them as active ingredients.COPYRIGHT: (C)2014,JPO&INPIT【課題】過活動膀胱等の膀胱障害の予防又は改善に有効なTRPV4活性抑制剤の提供。【解決手段】イソラムネチン、カテキン、ヘスペレチン、ケルセチン、ルテオリン、フィセチン、クリシン、ゲニステイン及びそれらの配糖体から選ばれるフラボノイド類を有効成分とするTRPV4活性抑制剤。【選択図】なし
