PROBLEM TO BE SOLVED: To provide a TRPV4 (Transient receptor potential cation channel subfamily V member 4) activity inhibitor, and an overactive bladder preventing or improving agent which utilizes the efficacy of the TRPV4 activity inhibitor and serves as means for administration thereof.SOLUTION: A TRPV4 activity inhibitor comprises piperine as an active ingredient. There is also provided an overactive bladder preventing or improving agent.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】TRPV4(Transient receptor potential cation channel subfamily V member 4)活性阻害剤、及びTRPV4活性阻害剤の効能を生かし、またその投与の手段としての、過活動膀胱の予防又は改善剤を提供する。【解決手段】ピペリンを有効成分とする、TRPV4活性阻害剤、又は過活動膀胱の予防若しくは改善剤。【選択図】なし
