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Competitive modulation of microRNAs
专利权人:
发明人:
Xue-hai Liang,Stanley T. Crooke
申请号:
US14651344
公开号:
US09695475B2
申请日:
2013.12.11
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides compounds and methods for competitive modulation of microRNAs. Such compounds and methods have profound effects on cells. MicroRNAs (microRNAs), are small (approximately 18-24 nucleotides in length), non-coding RNA molecules encoded in the genomes of plants and animals. In certain instances, microRNAs regulate the expression of genes by binding to the 3′-untranslated regions (3′-UTR) of specific mRNAs. More than 1000 different microRNAs have been identified in plants and animals.
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