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SYSTEM AND METHOD FOR DETECTING AMYLOID PROTEINS
专利权人:
发明人:
HARTUNG PAUL D,VALVO VINCENT,KERBAGE CHARLES,CAGLE GERALD D,NILAN DENNIS J
申请号:
IN1121/DELNP/2013
公开号:
IN2013DN01121A
申请日:
2013.02.06
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
In accordance with an embodiment of the invention there is provided a device and method for detecting an amyloid protein in an eye of a mammal. A method comprises illuminating the eye with a light source having at least one of a wavelength property a polarization property or a combination thereof each appropriate to produce fluorescence in at least an amyloid binding compound when the amyloid binding compound is bound to the amyloid protein the amyloid binding compound having been introduced to the eye and specifically binding to the amyloid protein indicative of the amyloidogenic disorder and determining a time decay rate of fluorescence for at least the fluorescence produced by the amyloid binding compound bound to the amyloid protein the determining permitting distinguishing of the presence of the amyloid binding compound bound to the amyloid protein in the eye based on at least the time decay rate.
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