The invention relates to a method for manufacturing and machining dental, maxillofacial and trauma prostheses that comprises: manufacturing (100), by using excess material and additive manufacturing technology on a printing plate (2), a prosthetic block (5A, 5B), which comprises at least a prosthesis (1), joining pieces (4A, 4B) and positioning elements (3A, 3B) with specific dimensions and distances between the same positioning the prosthetic block (5A, 5B) on a machining tray (103) by means of the positioning elements (3A, 3B) fixing the prosthetic block (5A, 5B) to the machining tray (104) by means of positioning elements (3A, 3B) fixing the machining tray (8) to a machining machine (105), such that the prosthesis (1) is fixed in a specific and known position in the machining machine, by the specific dimensions and distances of the prosthetic block (5A, 5B) and performing a machining operation to the critical areas of the prosthesis (106).