Production and diffusion cartridge of an aerosol (1) comprising a container (12) container of a liquid to be nebulized, a two-phase nebulizer nozzle (5) in relation to communication with the tank (12) through an internal channel ( 4a) of a suction cannula (4) and an air compressor (6) capable of producing a stream of compressed carrier air introduced into the biphasic nozzle (5) so that the contents of the reservoir, therein, are first aspirated by Venturi effect, divided below and finally propelled, first towards an expansion chamber (13) and then outwards, always by the carrier air stream, characterized in that the elements that constitute it are configured in a set not removable and because it includes means of programmed obsolescence suitable to determine directly or indirectly the total amount of liquid consumed in the previous operating cycles, suitable for comparison this value with a setpoint value representative of the amount of liquid present in the tank before the first use, and suitable to prohibit the subsequent operation of the compressor from the same exhaustion of the liquid contained in the tank (12), in order to make said cartridge unusable even if the latter's tank is refilled.Cartucho de producción y de difusión de un aerosol (1) que comprende un depósito (12) contenedor de un líquido que ha de nebulizarse, una boquilla bifásica nebulizadora (5) en relación de comunicación con el depósito (12) por un canal interno (4a) de una cánula de aspiración (4) y un compresor de aire (6) apto para producir una corriente de aire comprimido portadora introducida en la boquilla bifásica (5) con el fin de que el contenido del depósito, en ella, sea primero aspirado por efecto Venturi, fraccionado a continuación y, finalmente, propulsado, primero hacia una cámara de expansión (13) y a continuación hacia el exterior, siempre por la corriente de aire portadora, caracterizado por que los elementos que lo constituyen se configuran en un conjunto no desmontable y por