骨リモデリングのプロセスと関係があるポリヌクレオチドおよびポリペプチド配列

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专利权人:

アレシア・バイオセラピューティクス・インコーポレーテッド

发明人:

ロイ・ラビンドラノース・スークナナン,ジル・ベルナール・トランブレ,マリオ・フィリヨン

申请号：

JP2008553592

公开号：

JP5173838B2

申请日:

2007.02.13

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

This invention relates, in part, to unique and newly identified genetic polynucleotides involved in the process of bone remodeling, variants and derivatives of the polynucleotides and corresponding polypeptides, uses of the polynucleotides, polypeptides, variants and derivatives, and methods and compositions for the amelioration of symptoms caused by bone remodeling disorders. Disclosed in particular are the isolation and identification of polynucleotides polypeptides variants and derivatives involved in osteoclast activity, validation of the identified polynucleotides for their potential as therapeutic targets and use of the polynucleotides, polypeptides, variants and derivatives for the amelioration of disease states and research purposes.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/