New indazolcarboxamides, procedure for their preparation, pharmaceutical preparations containing them, as well as their use for the preparation of medicines

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专利权人:

Bayer Pharma Aktiengesellschaft

发明人:

BOTHE, Ulrich,SIEBENEICHER, Holger,SCHMIDT, Nicole,ROTGERI, Andrea,BÖMER, Ulf,RING, Sven,IRLBACHER, Horst,GÜNTHER, Judith,STEUBER, Holger,LANGE, Martin,SCHÄFER, Martina

申请号：

ES14824414

公开号：

ES2677996T3

申请日:

2014.12.16

申请国别(地区):

ES

年份:

2018

代理人:

摘要：

Compounds of general formula (I) ** Formula ** in which: R0 represents hydrogen or C1-C4 alkyl, the C1-C4 alkyl moiety may be substituted if necessary once or several times, in the same or different manner with hydroxy or halogen； R1 represents hydrogen, halogen, cyano, C (>； = O) OH, C (>； = O) ORa, C (>； = O) NH2, C (>； = O) N (H) Ra, C (>； = O) N (Ra) Rb, C (>； = O) Rd, hydroxy or C1-C6 alkyl, the C1-C6 alkyl moiety may be substituted once or several times, equally or differently with hydroxy, halogen, cyano, C (>； = O) OH, C (>； = O) ORa, S (>； = O) 2-C1-C6 alkyl, NH2, NHRa, N (Ra) Rb, a substituted C1-C6 alkoxy if necessary one or several times, in the same or different manner with halogen, a C3-C8 substituted cycloalkoxy, if necessary, once or several times, in the same or different manner with halogen, a heterocycloalkyl substituted once or several times, in the same or different manner with Rc, or represents C1-C6 alkoxy, the C1-C6 alkoxy moiety may be substituted, if necessary, one or more times, in the same or different manner with hydroxy, halogen, cyano, C (>； = O) OH, C (>； = O) ORa , S (>； = O) 2-C1-C6 alkyl, NH2, NHRa, N (Ra) Rb, a substituted C3-C8 cycloalkyl, if necessary one or several times, in the same or different manner with halogen, a C1- alkoxy C6 replaced if necessary one or several times, in the same or different manner with halogen, a C3-C8 substituted cycloalkoxy, if necessary once or several times, in the same or different manner with halogen, a substituted heterocycloalkyl, if necessary one or more times, of in the same or different form with Rc, a substituted aryl if necessary once or several times, in the same or different way with Rc or a substituted 5 or 6-membered heteroaryl, if necessary once or several times in the same or different way with Rc, or represents C3-C8 cycloalkoxy or heterocycloalkoxy, which may be substituted, if necessary, one or more times, in the same or different manner with hydroxy, halo

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