PROCEDE DE PRODUCTION D'UNE PREPARATION A BASE DE HOUBLON, PREPARATION A BASE DE HOUBLON AINSI OBTENUE, AGENT ANTI-INFLAMMATOIRE, ALIMENT/BOISSON ET PRODUIT PHARMACEUTIQUE PAR VOIE ORALE
A method for producing a preparation that can be used in the prevention and treatment of inflammatory diseases, including periodontitis caused by P. gingivalis. Specifically, the invention provides a method for producing a hop preparation comprising the following steps (1) to (3): (1) adjusting the pH of a polyphenol-containing liquid prepared from hop bracts to 6 to 7 and passing the liquid through a gel-type synthetic resin to allow components including useful substances to be adsorbed onto the resin； (2) washing the resin obtained in the step (1) with a 30 to 60% aqueous ethanol solution to elute unwanted substances, leaving the useful substances adsorbed to the resin； and (3) washing the resin obtained in the step (2) with a 70% or higher aqueous ethanol solution or ethanol to elute the components including the useful substances and forming the preparation from the eluted fraction.
