The invention is directed to a composition comprising: a polyurethane substrate； a hydrogel forming polymer on at least one of the two faces of the polyurethane substrate； and chlorhexidine on the at least one face comprising the hydrogel forming polymer； wherein the hydrogel polymer is covalently linked to the polyurethane substrate. The invention is also directed to a dressing in comprising the composition and to a process for the preparation of the composition, the process comprising the following steps: a) in impregnating at least one face of a polyurethane substrate with a solution comprising a reactive diolefin and a free radical initiator； b) extracting the polyurethane from the solution and, after drying, immerging the polyurethane in a solution containing the initiator catalyst and the hydrogel forming polymer to obtain PU covalently bond to a hydrogel forming polymer； c) extracting the polyurethane-hydrogel composition and drying in air； d) immerging the product of step iii) into an aqueous solution of chlorhexidine； e) collecting the polyurethane-hydrogel-chlorhexidine product from the solution and drying the obtained composition in air.
