Lynn Macdonald,Andrew J. Murphy,Naxin Tu,Vera Voronina,Cagan Gurer
申请号：
US15727057
公开号：
US20180084768A1
申请日:
2017.10.06
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides genetically modified non-human animals that express chimeric human/non-human T cell co-receptor polypeptides (e.g., CD4, CD8α, CD8β), as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same.
