MACDONALD, LYNN,MURPHY, ANDREW J.,TU, NAXIN,VORONINA, VERA,GURER, CAGAN
申请号：
PL14708430
公开号：
PL2958938T3
申请日:
2014.02.20
申请国别(地区):
PL
年份:
2019
代理人:
摘要：
The invention provides genetically modified non-human animals that express chimeric human/non-human T cell co-receptor polypeptides (e.g. CD4, CD8α, CD8β), as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same.
