To provide a vesicle-containing composition which recovers the lamellar structure of an intercellular lipid, can improve the horny layer barrier function, and has excellent temporal stability.SOLUTION: The composition contains a vesicle which comprises a mannosylerythritol lipid represented by the general formula (1) in the figure and a specific alkyl glycoside. (In general formula (1), Rand Reach independently represent a C6-20 acyl group, and Rand Reach independently represent an acetyl group or hydrogen atom.)SELECTED DRAWING: None【課題】細胞間脂質のラメラ構造を回復させ、角層バリア機能を向上させることができ、かつ経時安定性に優れるベシクル含有組成物の提供。【解決手段】下記一般式(1)で表されるマンノシルエリスリトールリピッドと、特定のアルキルグリコシドを含むベシクルを含有する組成物。(一般式(1)において、R1及びR2は独立して炭素数6~20のアシル基を表し、R3及びR4は独立してアセチル基又は水素原子を表す。)【選択図】なし