Claim 1: A compound of the formula (1) wherein: R¹ is halogen, cycloalkylalkoxy, haloalkoxy, alkylsulfonyl, alkylsulfinyl, halophenyl alkyl, alkylsulfanyl, oxanylalkoxy, halophenyl or oxolanylalkoxy； R² is halogen, cycloalkyl, haloalkyl, haloalkoxy, haloazetidinyl, cycloalkyloxy, halocycloalkyl, hydroxycycloalkyl, hydroxyazetidinyl, hydroxyoxetanyl or halooxetanyl； R³ is (alkyl) (oxo) pyrrolidinyl or -C (R⁴R⁵) -C (R⁶R⁷) -C (O) -R⁸；R⁴ and R⁵ are independently selected from hydrogen, alkyl, phenyl, phenylalkyl, cycloalkyl, tetrahydropyranyl, haloalkyl, halophenyl and oxolanyl； or R⁴ and R⁵ together with the carbon atom to which they are attached form a cycloalkyl, oxetanyl, tetanyl, 1,1-dioxo-1-6-thiethanyl, azetidinyl, haloazetidinyl, 2-oxa-spiro [3.3] -heptyl, tetrahydrofuranyl, pyrrolidinyl , oxopyrrolidinyl, 1,1-dioxo-1l6-isothiazolidinyl, 1,1-dioxo-tetrahydro-1l6-thiophenyl, tetrahydrothiophenyl, tetrahydropyranyl, piperidinyl, oxopiperidinyl, tetrahydrothiopyranyl, 2-oxo- [1,3] -oxazinanyl, 1,1 -dioxo-1l6- [1,2] thiazinanyl, 2-oxo-hexahydro-pyrimidinyl, 1,1-dioxo-hexahydro-1l6-thiopyranyl,2-dioxo - [1.3] dioxy, 1,1-dioxy, tar cornerstone, tar base benzene, phenylmethoxyethane, oxolanilo or phenylformate glycol dioxy； r8310 and r8311811 should be selected independently between hydrogen and tar； or 1-r83080 and r83099, 1-r8310 and r8311811；It forms a cyclopentanediol together with carbon atom, and the rest is the same hydrogen in both cases； r831222 es-nh832222；4. Alcoxi, rental or hydroxy； or a salt or ester acceptable for drugs.Reivindicación 1: Un compuesto de la fórmula (1) en la que: R¹ es halógeno, cicloalquilalcoxi, haloalcoxi, alquilsulfonilo, alquilsulfinilo, halofenilalquilo, alquilsulfanilo, oxanilalcoxi, halofenilo u oxolanilalcoxi； R² es halógeno, cicloalquilo, haloalquilo, haloalcoxi, haloazetidinilo, cicloalquiloxi, halocicloalquilo, hidroxicicloalquilo, hidroxiazetidinilo, hidroxioxetanilo o halooxetanilo； R³ es (alquil)(oxo)pirrolidinilo o -C(R⁴
