SCHMEES, NORBERT,HAENDLER, BERNARD,STOCKIGT, DETLEF,GALLENKAMP, DANIEL,BISSELL, RICHARD ALEXANDER,BOUGLAS, RICHARD ALEXANDER
申请号：
CA2917562
公开号：
CA2917562A1
申请日:
2014.07.07
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The invention relates to BET-protein-inhibiting, in particular BRD4-inhibiting, dihydroquinoxalinones and dihydropyridopyrazinones of general formula (I), in which A, X, R1, R2, R3, R4, R5, R6, and n have the meanings indicated in the description, intermediate products for producing the compounds according to the invention, pharmaceutical agents containing the compounds according to the invention, and the prophylactic and therapeutic use of said pharmaceutical agents in the case of hyperproliferative diseases, in particular in the case of tumor diseases. The invention further relates to the use of BET protein inhibitors in the case of viral infections, neurodegenerative diseases, inflammatory diseases, and atherosclerotic diseases and in male fertility control.
