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PHENYL-2,3-BENZODIASEPINE SUBSTITUEE
专利权人:
BAYER PHARMA AKTIENGESELLSCHAFT
发明人:
SIEGEL, STEPHAN,BAURLE, STEFAN,CLEVE, ARWED,HAENDLER, BERNARD,FERNANDEZ-MONTALVAN, AMAURY ERNESTO,MONNING, URSULA
申请号:
CA2915419
公开号:
CA2915419A1
申请日:
2014.06.17
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The invention relates to BET-protein-inhibiting, in particular BRD4-inhibiting, substituted phenyl-2,3-benzodiazepines of general formula (I), in which X, R1a, R1b, R1c, R2, R3, R4, and R5 have the meanings specified in the description, to pharmaceutical agents containing the compounds according to the invention, and to the prophylactic and therapeutic use of said pharmaceutical agents for hyperproliferative diseases, in particular tumor diseases. The invention further relates to the use of BET protein inhibitors in benign hyperplasias, atherosclerotic diseases, sepsis, autoimmune diseases, vascular diseases, viral infections, neurodegenerative diseases, inflammatory diseases, atherosclerotic diseases, and male fertility control.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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