A juice extraction module for a large-caliber juicer includes a base, a hood body, a rotary brush, a juicing net and a helical structure, wherein the hood body is matched with the base the rotary brush, the juicing net and the helical structure are accommodated in a housing formed by matching the base and the hood body the helical structure is accommodated in the juicing net the juicing net is accommodated in the rotary brush and an outer wall of the juicing net is fitted with an inner wall of the rotary brush. An extrusion part is arranged on the helical structure of the juice extraction module for the large-caliber juicer in the utility model. Helical vanes are arranged at the periphery of the extrusion part. Outer diameters of the helical vanes are consistent from top to bottom. A cutting part is arranged at a top of the extrusion part. The cutting part firstly cuts fruits and vegetables into small blocks the helical vanes continuously deliver the small blocks of the fruits and vegetables downwards and extrude the small blocks, so as to realize quick juicing, thereby effectively preventing the fruits and vegetables from accumulating in a feed inlet and increasing juicing efficiency.