СИН Мюн Чжин (KR),ЧЖИН Хон Чул (KR),ПАРК Юн Чжоон (KR),ЧОЙ Нак Хюн (KR),ЧОЙ Ха Ён (KR)
申请号:
RU2015149114
公开号:
RU2015149114A
申请日:
2014.05.08
申请国别(地区):
RU
年份:
2017
代理人:
摘要:
The present invention relates to a stabilized pemetrexed formulation, and more specifically, to a stabilized pemetrexed formulation comprising acetylcysteine as an antioxidant and sodium citrate as a buffering agent. Additionally, the present invention relates to a pemetrexed formulation filled in a sealed container, comprising pemetrexed or a pharmaceutically acceptable salt thereof as an active ingredient, wherein the oxygen gas content within the headspace of the container is 3 v/v% or less.