SHIN, Myung Jin,JIN, Hong Chul,PARK, Young Joon,CHOI, Nak Hyun,CHOI, Ha Yong
申请号：
PH12015502542
公开号：
PH12015502542B1
申请日:
2015.11.06
申请国别(地区):
PH
年份:
2016
代理人:
摘要：
The present invention relates to a stabilized pemetrexed formulation, and more specifically, to a stabilized pemetrexed formulation comprising acetylcysteine as an antioxidant and sodium citrate as a buffering agent. Additionally, the present invention relates to a pemetrexed formulation filled in a sealed container, comprising pemetrexed or pharmaceutically acceptable salt thereof as an active ingredient, wherein the oxygen gas content within the headspace of the container is 3 v/v pcnt or less.
