SHIN, Myung Jin,JIN, Hong Chul,PARK, Young Joon,CHOI, Nak Hyun,CHOI, Ha Yong,申明珍,秦宏澈,朴映准,崔洛鉉,崔河龍
申请号:
HK16106166.7
公开号:
HK1218076A
申请日:
2016.05.31
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
The present invention relates to a stabilized pemetrexed formulation, and more specifically, to a stabilized pemetrexed formulation comprising acetylcysteine as an antioxidant and sodium citrate as a buffering agent. Additionally, the present invention relates to a pemetrexed formulation filled in a sealed container, comprising pemetrexed or a pharmaceutically acceptable salt thereof as an active ingredient, wherein the oxygen gas content within the headspace of the container is 3 v/v% or less.