SPENCER, DAVID M.,BAYLE, JOSEPH HENRI,FOSTER, AARON EDWARD,SLAWIN, KEVIN M.,MOSELEY, ANNEMARIE B.,COLLINSON-PAUTZ, MATTHEW R.,DUONG, MYLINH
申请号:
CA2966241
公开号:
CA2966241A1
申请日:
2015.12.14
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The technology relates in part to methods for controlling the activity or elimination of therapeutic cells using multimerization of proteins to manipulate individual protein- protein interactions in therapeutic cells, for example, by activating or eliminating cells used to promote engraftment, to treat diseases or condition, or to control or modulate the activity of therapeutic cells that express chimeric antigen receptors or recombinant T cell receptors.