INHIBITORY BETA-SEKRETAZY

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专利权人:

发明人:

BUKHTIYAROV YURI,CACATIAN SALVACION,DILLARD LAWRENCE WAYNE,DORNER-CIOSSEK CORNELIA,FUCHS KLAUS,JIA LANQI,LALA DEEPAK S.,MORALES-RAMOS ANGEL,RAST GEORG,REEVES JONATHAN,SINGH SURESH B.,VENKATRAMAN SHANK

申请号：

PL13710937

公开号：

PL2822930T3

申请日:

2013.03.04

申请国别(地区):

PL

年份:

2016

代理人:

摘要：

The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the &bgr；-secretase enzyme (BACE1) activity, pharmaceutical compositions containing the same, and methods of using the same as therapeutic agents in the treatment of neurodegenerative disorders, disorders characterized by cognitive decline, cognitive impairment, dementia and diseases characterized by production of &bgr；-amyloid aggregates.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/