Bioengineered collagen constructs with antimicrobial properties is provided. Sheet-like layer of purified collagen organization of the tissue source from such of the submucosal layer of the small intestine, or bioengineered collagen construct, including the processed intestinal collagen layer of the submucosal layer of the small intestine derived from that has been treated with an antimicrobial agent. Construct is biocompatible. The present invention has a variety of applications including surgical repair device and wound dressing. A method of treating a disease soft tissue is provided or soft tissue damage. Method of treating a wound in need of treatment are also disclosed and care.抗菌特性を有する生物工学処理コラーゲン構築物が提供される。生物工学処理コラーゲン構築物は、小腸の粘膜下層のような組織源由来の精製コラーゲン組織のシート様層、又は抗菌剤で処理された小腸の粘膜下層由来の処理済み腸コラーゲン層を含む。構築物は生体適合性である。本発明は、創傷被覆剤及び外科用修復デバイスを含めた種々の用途を有する。損傷柔組織又は疾患柔組織の治療方法が提供される。ケア及び治療を必要とする創傷の治療方法も開示される。
