SZETO, HAZEL H.,BIRK, ALEXANDER V.,ROZENBERG, FELIX
申请号:
CA2925475
公开号:
CA2925475A1
申请日:
2014.09.26
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present disclosure provides aromatic-cationic peptide compositions and methods of using the same. The methods comprise use of the peptides in inhibiting cholesterol-induced cytochrome c peroxidase activity, promoting reduction of cytochrome c, and inhibition of cardiolipin peroxidation to treat, prevent or ameliorate cholesterol-induced mitochondrial dysfunction.