Use of aromatic-cationic peptides to treat cholesterol-induced mitochondrial dysfunction

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专利权人:

Cornell University;Felix Rozenberg

发明人:

Rozenberg, Felix,Szeto, Hazel H.,Birk, Alexander V.

申请号：

AU2014324705

公开号：

AU2014324705A1

申请日:

2014.09.26

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The present disclosure provides aromatic-cationic peptide compositions and methods of using the same. The methods comprise use of the peptides in inhibiting cholesterol-induced cytochrome c peroxidase activity, promoting reduction of cytochrome c, and inhibition of cardiolipin peroxidation to treat, prevent or ameliorate cholesterol-induced mitochondrial dysfunction.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/