YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.;ATOX BIO LTD.
发明人:
KAEMPFER, RAYMOND,SHIRVAN, ANAT,ARAD, GILA
申请号:
CA2932150
公开号:
CA2932150A1
申请日:
2014.12.07
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present disclosure relates to a method for the treatment of a non-pathogen associated inflammatory disorders in a subject in need thereof, comprising administering to said subject an isolated peptide which specifically binds to an amino acid sequence within the dimer interface of a T cell costimulatory pathway member, particularly the T cell costimulatory pathway members CD28 and CTLA4. The present disclosure also relates to pharmaceutical compositions comprising the isolated peptide and to use of the peptide in treating of a non-pathogen associated inflammatory disorders.