HOUNG, JER YIING,洪哲颖,洪哲穎,HSU, HSIA FEN,许夏芬,許夏芬,CHEN, ZI HUA,陈姿桦,陳姿樺,CHANG, SHIH FAN,张师凡,張師凡
申请号:
TW100145600
公开号:
TW201322989A
申请日:
2011.12.09
申请国别(地区):
TW
年份:
2013
代理人:
摘要:
An inhibitor for inhibiting metastasis of cancer cell comprises an extract of Anisomeles indica, which can inhibit the migration and invasion of the cancer cell. The extract of Anisomeles indica is made from the method below: a drying step, providing and drying an aboveground portion of Anisomeles indica until the water content is below 10%, and obtaining a dry Anisomeles indica a first extraction step, extracting the dry Anisomeles indica by ethanol and obtaining an ethanol extract a second extraction step, extracting the ethanol extract by hexane and obtaining a hexane extracting liquid a concentration step, concentrating the hexane extracting liquid and obtaining the extract of Anisomeles indica. A medication of inhibiting metastasis of cancer cell comprises an extract of Anisomeles indica and at least a medically acceptable adjuvant or carrier.一種癌細胞轉移抑制劑,係包含具有抑制癌細胞移行及入侵作用之魚針草萃取物,該魚針草萃取物係由下列步驟製備而得:一乾燥步驟,將一魚針草地上部進行乾燥,使該魚針草葉部之含水量降至10%以下,得到一魚針草乾燥物;一第一萃取步驟,係以乙醇溶劑萃取該魚針草乾燥物,得到一乙醇萃取液,將該乙醇萃取液乾燥形成一乙醇萃取物;一第二萃取步驟,以正己烷溶劑萃取該乙醇萃取物,獲得一正己烷萃取液;及一濃縮步驟,係將該正己烷萃取液進行濃縮,獲得一魚針草萃取物。一種抑制轉移性癌細胞之醫藥組合物,係包含魚針草萃取物,及至少一種醫藥可接受之藥物佐劑或藥物載劑。S1...乾燥步驟S2...第一萃取步驟S3...第二萃取步驟S4...濃縮步驟